Multienzyme Cascade Bioreactor for a 10 min Digestion of Genomic DNA into Single Nucleosides and Quantitative Detection of Structural DNA Modifications in Cellular Genomic DNA.

Identification and quantification of chemical modification of DNA provides important information about changes in genomic DNA, for example, epigenetic modifications and abnormal DNA lesions. In this layer, which is needed to digest the genomic DNA strands into a single nucleoside, facilitating mass spectrometry analysis. However, the rapid digestion of DNA as supramacromolecule of several million Dalton (molecular weight) into a single nucleoside remains very challenging.

Here, we constructed a bioreactor Benzonase move capillaries and subsequently immobilized tandem coupled with snake venom phosphodiesterase and alkaline phosphatase capillary bioreactor to form a novel three-enzyme cascade bioreactor (BenzoSAC bioreactor). In this construction, the enzyme selected moving to synthetic porous monolithic silica capillary.

With tailor-made porous structure and high immobilized capacity and high-level Benzonase digestion, genomic DNA of> 99.5% can be digested into a single nucleoside within just 10 minutes when passing through the bioreactor BenzoSAC by the injection pump. In contrast, traditional digestion requires 8-24 hours. With offline clutch benzoSAC bioreactor with chromatography-tandem mass spectrometry liquid, we detected a 5-hydroxymethylcytosine, the main oxidation product of epigenetically importance of 5-methylcytosine in genomic DNA isolated from cancer stairs (T24) cells. The BenzoSAC bioreactor newly synthesized and proposed mass spectrometry detection promising for the rapid identification and analysis of structural modifications in DNA.


Viruses that infect thermophilic Archaea that is unique in both structure and genetics. Lemon-shaped fuselloviruses that infects members of the order Sulfolobales, grows optimally at 80 ° C and pH 3-are some viruses that most ubiquitous and best studied of Archaea thermoacidophilic. Nonetheless, there is still much to be learned about this virus. In order to investigate the evolution of fusellovirus, we have isolated and characterized a new fusellovirus, Sulfolobus spindle-shaped virus 10 (previously SSV-L1). Comparative genomic analysis highlights the significant similarities with both SSV8 and SSV9, as well as the conservation of promoter elements in Fuselloviridae.

 Multienzyme Cascade Bioreactor for a <em>10</em> min Digestion of <em>Genomic</em> DNA into Single Nucleosides and Quantitative Detection of Structural DNA Modifications in Cellular <em>Genomic</em> DNA.
Multienzyme Cascade Bioreactor for a 10 min Digestion of Genomic DNA into Single Nucleosides and Quantitative Detection of Structural DNA Modifications in Cellular Genomic DNA.

Comparison of genomic and transcriptome analysis of Lactobacillus rhamnosus ATCC 11443 and mutant strains SCT- 10 – 10 -60 to increase the production capacity of L-lactic acid.

The mechanism for the production of L-lactic acid of high remains unclear in many bacteria. Lactobacillus rhamnosus-10-10-60 SCT previously obtained from L. rhamnosus ATCC 11443 by mutagenesis and showed increased production of L-lactic acid. In this study, genome-10-10-60 SCT strain and ATCC 11443 were sequenced.

The second genome is a circular chromosome, 2.99 Mb long with a GC content of about 46.8%. Eight split genes identified in strain-10-10-60 SCT, including two LytR family of transcriptional regulators, two Rex redox-sensing transcriptional repressor, and four ABC transporters. In total, 60 genes were significantly up-regulated (log2fold-change ≥ 2) and 39 significantly down-regulated genes (log2fold-change ≤ – 2) were identified by transcriptome comparison between SCT-10-10-60 strain and ATCC 11443. KEGG pathway enrichment analysis revealed that “pyruvate metabolism” significantly different (P <0.05) between the two strains.

Anti- Cytochrome P450 2C11 Antibody

GWB-2D2E2C 0.1 ml Ask for price

Anti- Cytochrome b5 Rabbit Antibody

GWB-E6C3AB 0.1 ml Ask for price

Cytochrome c Antibody

8C0170 50ug
EUR 368
Description: Cytochrome c Antibody

Cytochrome C antibody

10R-8465 100 ul
EUR 471.6
Description: Mouse monoclonal Cytochrome C antibody

Cytochrome C antibody

10R-6609 100 ug
EUR 398
Description: Mouse monoclonal Cytochrome C antibody

Cytochrome B5 antibody

20R-CG009 100 ul Ask for price
Description: Goat polyclonal Cytochrome B5 antibody

Cytochrome C Antibody

21680 100ul
EUR 319

Cytochrome C Antibody

21680-100ul 100ul
EUR 302.4

Cytochrome C Antibody

21680-50ul 50ul
EUR 224.4

Cytochrome c antibody

20R-1430 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1518 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1519 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c Antibody

3025-100 each
EUR 438

Cytochrome c Antibody

3025-30T each
EUR 175.2

Cytochrome c Antibody

33354 100ul
EUR 319

Cytochrome c Antibody

33354-100ul 100ul
EUR 302.4

Cytochrome c Antibody

33354-50ul 50ul
EUR 224.4

Cytochrome c Antibody

3352-100 each
EUR 379.2

Cytochrome c Antibody

3352-30T each
EUR 175.2

Cytochrome c Antibody

3353-100 each
EUR 379.2

Cytochrome c Antibody

3353-30T each
EUR 175.2

Cytochrome C Antibody

48927 100ul
EUR 499

Cytochrome C Antibody

48927-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48927-50ul 50ul
EUR 286.8

Cytochrome C Antibody

48976 100ul
EUR 499

Cytochrome C Antibody

48976-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48976-50ul 50ul
EUR 286.8

cytochrome b Antibody

39342-100ul 100ul
EUR 468

Cytochrome b5 Antibody

abx232186-100ug 100 ug
EUR 577.2

Cytochrome c Antibody

E033354 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome C Antibody

E021680 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome c Antibody

E11-0170C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome C Antibody

DF6028 200ul
EUR 420

Cytochrome C Antibody

DF6028-100ul 100ul
EUR 280

Cytochrome C Antibody

DF6028-200ul 200ul
EUR 350

Cytochrome c Antibody

E38PA6018 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA9145 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA2689 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c1 Antibody

E38PA4382 100ul
EUR 225
Description: Available in various conjugation types.

cytochrome b Antibody

E301343 100ug/200ul
EUR 275
Description: Available in various conjugation types.

Cytochrome C antibody

BF0714 200ul
EUR 540

Cytochrome C antibody

BF0714-100ul 100ul
EUR 350

Cytochrome C antibody

BF0714-200ul 200ul
EUR 450

Cytochrome C antibody

BF0714-50ul 50ul
EUR 250

Cytochrome c antibody

70R-13781 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11564 100 ug
EUR 406
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11766 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11767 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome C antibody

70R-31158 100 ug
EUR 294
Description: Rabbit polyclonal Cytochrome C antibody

Cytochrome C antibody

70R-51008 100 ul
EUR 242
Description: Purified Polyclonal Cytochrome C antibody

Cytochrome C Antibody

AF0146 200ul
EUR 420

Cytochrome C Antibody

AF0146-100ul 100ul
EUR 280

Cytochrome C Antibody

AF0146-200ul 200ul
EUR 350

Cytochrome C Antibody

AF7004 200ul
EUR 540

Cytochrome C Antibody

AF7004-100ul 100ul
EUR 350

Cytochrome C Antibody

AF7004-200ul 200ul
EUR 450

Cytochrome C Antibody

AF7004-50ul 50ul
EUR 250

Cytochrome c Antibody

ABF7004 100 ug
EUR 525.6

Cytochrome c Antibody

ABF0146 100 ug
EUR 525.6

Cytochrome C Antibody

GWB-56035A 0.1 mg Ask for price

Cytochrome C, Antibody

GWB-5AC847 1 ml Ask for price

Cytochrome C, Antibody

GWB-83C84A 7 ml Ask for price

Cytochrome C Antibody

GWB-F62EAD 0.1 mg Ask for price

Cytochrome C Antibody

GWB-CE42EA 0.05 mg Ask for price

Cytochrome c antibody

PAab098271 100 ug
EUR 463.2

Cytochrome C Antibody

R32947 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

R31747 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

RQ4499 100ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

V8015-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2785-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785-20UG 20 ug
EUR 186.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2786-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786-20UG 20 ug
EUR 186.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786IHC-7ML 7 ml
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786SAF-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2788-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2789-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789-20UG 20 ug
EUR 186.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome b5 Antibody

abx232186-100g 100 µg
EUR 350

Cytochrome C antibody (FITC)

61R-1166 100 ug
EUR 564
Description: Mouse monoclonal Cytochrome C antibody (FITC)

Cytochrome C1 Antibody / CYC1

F54386-0.08ML 0.08 ml
EUR 140.25
Description: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

Cytochrome C1 Antibody / CYC1

F54386-0.4ML 0.4 ml
EUR 322.15
Description: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

Human Cytochrome B5 Antibody

33293-05111 150 ug
EUR 215

Anti- Cytochrome P450 2A6 Human/Rat Antibody

GWB-2842F9 0.1 ml Ask for price

Anti-CYP2C19/Cytochrome P450 2C19 Antibody

A02102 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CYP2C19 Antibody (CYP2C19) detection.tested for WB in Human.

Rabbit anti Cytochrome C Polyclonal Antibody

TA354160 100 µg Ask for price

Cytochrome b5A Antibody

20-abx009370
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  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome b5B Antibody

E38PA5454 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome b5A Antibody

E38PA1305 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome b5A antibody

70R-49624 100 ul
EUR 242
Description: Purified Polyclonal Cytochrome b5A antibody

Cytochrome b561 Antibody

20-abx149642
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  • 100 ug
  • 50 ug

Cytochrome p450 antibody

20R-1445 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome p450 antibody

Cytochrome P450 Antibody

3084R-100 each
EUR 379.2

Cytochrome P450 Antibody

3084R-30T each
EUR 175.2

Cytochrome b561 Antibody

45603-100ul 100ul
EUR 302.4

Cytochrome b561 Antibody

45603-50ul 50ul
EUR 224.4

Cytochrome b561 Antibody

E19-8938-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

Cytochrome b561 Antibody

E19-8938-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome b561 Antibody

DF8938 200ul
EUR 420

Cytochrome b561 Antibody

DF8938-100ul 100ul
EUR 280

Cytochrome b561 Antibody

DF8938-200ul 200ul
EUR 350

Cytochrome P450 antibody

70R-11598 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome P450 antibody

Cytochrome b561 Antibody

ABD8938 100 ug
EUR 525.6

Cytochrome C Antibody Cocktail

V2790-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Anti- Cytochrome P450 Enzyme CYP3A2 Rat Antibody

GWB-19A747 0.1 ml Ask for price

Anti- Cytochrome P450 Enzyme CYP2E1 Rat Antibody

GWB-1CC040 0.1 ml Ask for price

Anti- Cytochrome P450 Enzyme CYP3A1 Rat Antibody

GWB-73E710 0.1 ml Ask for price

Anti- Cytochrome P450 Enzyme CYP2D1 Rat Antibody

GWB-E6414A 0.1 ml Ask for price

Polyclonal Cytochrome c Antibody

APR00077G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cytochrome c . This antibody is tested and proven to work in the following applications:

Polyclonal Cytochrome c Antibody

APR07477G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cytochrome c . This antibody is tested and proven to work in the following applications:

Anti- Cytochrome P450 CYP4A1/2/3 Rat Antibody

GWB-B96FC1 0.1 ml Ask for price

Rat Cytochrome Antibody (P450 2E1)

GWB-1E01AF 10 Blots Ask for price

Positive Control for Anti-Human Cytochrome b5 Antibody

Cb5CON 100 uL
EUR 98

Cytochrome C IHC Antibody

IW-PA1118 -
EUR 285

Anti- Cytochrome P450 Enzyme CYP1A1 Human Antibody

GWB-A49895 0.1 ml Ask for price

Anti- Cytochrome P450 Enzyme CYP1A2 Human Antibody

GWB-E1F877 0.1 ml Ask for price

Cytochrome P450 21 Antibody

ABD4752 100 ug
EUR 525.6

Cytochrome C1 (CYC1) Antibody

20-abx110486
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cytochrome C1 (CYC1) Antibody

20-abx111915
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  • 150 ul
  • 50 ul

Cytochrome C1 (CYC1) Antibody

20-abx121883
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  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome C1 (CYC1) Antibody

20-abx125738
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Cytochrome C (CYCS) Antibody

20-abx134056
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  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome C (CYCS) Antibody

20-abx008130
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  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome C1 (CYC1) Antibody

abx032482-400ul 400 ul
EUR 627.6

Cytochrome C1 (CYC1) Antibody

abx032482-80l 80 µl
EUR 343.2

Cytochrome C1 (CYC1) Antibody

20-abx015080
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome P450 21 Antibody

20-abx015133
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome C1 (CYC1) Antibody

20-abx002770
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  • 100 ul
  • 200 ul

Cytochrome C (CYCS) Antibody

20-abx013057
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome C1 (CYC1) Antibody

abx026372-400ul 400 ul
EUR 627.6

Cytochrome C1 (CYC1) Antibody

abx026372-80l 80 µl
EUR 343.2

Cytochrome B5 (CYB5) Antibody

20-abx014018
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome C1 (CYC1) Antibody

abx232119-100ug 100 ug
EUR 577.2

Cytochrome C (CYCS) Antibody

abx232187-100ug 100 ug
EUR 610.8

Cytochrome C1 (CYC1) Antibody

20-abx325494
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  • 100 ug
  • 50 ug

Cytochrome C1 (CYC1) Antibody

abx330912-100ul 100 ul
EUR 510

Cytochrome b561 D1 Antibody

E11-12081C 100μg
EUR 225
Description: Available in various conjugation types.

Cytochrome P450 21 Antibody

E11-21034C 100μg
EUR 225
Description: Available in various conjugation types.

Cytochrome P450 21 Antibody

E19-4752 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c(cycs)Antibody

E90051 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome B ( NOX2 ), Antibody

GWB-DF4E97 1 mg Ask for price

Cytochrome C (CYCS) Antibody

abx013057-100g 100 µg
EUR 237.5

Gen split and differentially expressed genes involved in “pyruvate metabolism” pathway may be responsible for increasing the production of L-lactic acid by SCT-10-10-60. Genome and transcriptome sequencing information and comparison of SCT-10-10-60 with ATCC 11443 gives an insight into the L-lactic acid anabolism and references to increase the production of L-lactic acid using genetic engineering.