Genome-Wide Association Study Reveals Novel Genomic Regions Associated with 10 Grain Minerals in Synthetic Hexaploid Wheat.

Synthetic hexaploid wheat (SHW ;. Triticum durum × Aegilops tauschii L. Coss) is a means of introducing new genes / genomic region into bread wheat (T. aestivum L.) and genetic resources with the potential to increase the concentration of mineral grains. We counted 10 mineral grains (Ca, Cd, Cu, Co, Fe, Li, Mg, Mn, Ni, and Zn) using inductively coupled mass spectrometer at 123 SHWs for genome-wide association studies (GWAS). A GWAS with 35 648 single nucleotide polymorphism (SNP) markers identified 92 marker-trait association (MTA), of which 60 are novel and 40 were in the genes, and the genes that underlie 20 MTA has an explanation suggests a potential role in the concentration of mineral grains.

Twenty-four MTA on the new D-genome and shows the potential of Ae. tauschii to increase the concentration of mineral grains such as Ca, Co, Cu, Li, Mg, Mn, and Ni. Interestingly, a large number of MTA Novel (36) identified in the genome SHWs AB shows that there are many variations yet to be explored and used in the A and B genomes along with the D-genome. Regression analysis identified a positive correlation between the cumulative number of favorable alleles in MTA locus genotype in mineral concentration and grain. In addition, we identified a multi-trait and MTA stable and recommended 13 to 10% SHWs with a higher concentration of the mineral grains are beneficial (Cu, Fe, Mg, Mn, Ni, and Zn), a large number of beneficial alleles compared with low Ranked genotype and checks that can be utilized in breeding programs for genetic bio-fortification. This research will improve our understanding of the genetic architecture of mineral grains of wheat and related cereals.


The MLLT10 (formerly AF10) gene fusion KMT2A partner is the fourth most common in all acute leukemia and requires at least 3 break to form in-frame KMT2A / MLLT10 fusion because the opposite orientation of each gene. A 10-year retrospective conducted to identify individuals of all age groups who harbor KMT2A / MLLT10 fusion obtained with our KMT2A / MLLT10 dual-color dual-fusion fluorescence in situ hybridization (D-FISH) assay.

Of unique individuals 60 identified, 31 were male and 29 were female (M: F ratio, 1.1: 1) with ages ranging from 3 days to 86 years (mean 21.5 years, median 5.5 year). Diagnoses included acute myeloid leukemia (AML) (49 patients, 82%), B- or T-lymphoblastic leukemia / lymphoma (7 patients, 12%), myeloid sarcoma (3 patients, 5%), and one case (2%) differentiated leukemia.

 Genome-Wide Association Study Reveals Novel <em>Genomic</em> Regions Associated with <em>10</em> Grain Minerals in Synthetic Hexaploid Wheat.
Genome-Wide Association Study Reveals Novel Genomic Regions Associated with 10 Grain Minerals in Synthetic Hexaploid Wheat.

Comparison of genomic of 10 new Caenorhabditis species.

The nematode Caenorhabditis elegans has been central to understanding the biology of metazoan. However, C. elegans is just one species among millions and the importance of this important model organism will only be fully revealed when placed in the context of the evolution of the rich.

global sampling efforts have led to the discovery of more than 50 species of the genus Caenorhabditis suspected, many are waiting for the official description of the species. Here, we present a description of the species to 10 species of Caenorhabditis new. We also present a draft sequence of the genome of nine new species, along with the transcriptome assembly for one. We utilize whole genome data to reconstruct the phylogeny of Caenorhabditis and use these phylogenetic trees to dissect the evolution of morphology in the genus.

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) APC

MBS6137710-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) APC

MBS6137710-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (PE)

MBS6158922-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (PE)

MBS6158922-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (HRP)

MBS6153619-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (HRP)

MBS6153619-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (FITC)

MBS6148316-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (FITC)

MBS6148316-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (Biotin)

MBS6143013-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (Biotin)

MBS6143013-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 550)

MBS6212620-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 550)

MBS6212620-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 405)

MBS6191270-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 405)

MBS6191270-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 750)

MBS6233970-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 750)

MBS6233970-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 490)

MBS6201945-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 490)

MBS6201945-5x01mL 5x0.1mL
EUR 3800

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 650)

MBS6223295-01mL 0.1(mL
EUR 875

MT2A (Metallothionein-2, MT-2, Metallothionein-2A, Metallothionein-II, MT-II, CES1, MT2) (MaxLight 650)

MBS6223295-5x01mL 5x0.1mL
EUR 3800

Metallothionein-1

AP78817 1mg
EUR 2640

Metallothionein-2

AP79215 1mg
EUR 2640

Metallothionein-1

AP85694 1mg
EUR 2640

Metallothionein-1

AP85824 1mg
EUR 2640

Metallothionein-2

AP85825 1mg
EUR 2640

Metallothionein-2

AP85361 1mg
EUR 2640

Metallothionein-2

AP85471 1mg
EUR 2640

Metallothionein-1

AP86332 1mg
EUR 2640

Metallothionein-2

AP86333 1mg
EUR 2640

Metallothionein-1A

AP85358 1mg
EUR 2640

Metallothionein-1E

AP85359 1mg
EUR 2640

Metallothionein-2A

AP85475 1mg
EUR 2640

Metallothionein-1A

AP85506 1mg
EUR 2640

Metallothionein 3

PR27180 10 ug
EUR 184.5

Anti - METALLOTHIONEIN

MBS684009-002mL 0.02mL
EUR 270

Anti - METALLOTHIONEIN

MBS684009-005mL 0.05mL
EUR 405

Anti - METALLOTHIONEIN

MBS684009-01mL 0.1mL
EUR 590

Anti - METALLOTHIONEIN

MBS684009-5x01mL 5x0.1mL
EUR 2355

Metallothionein Antibody

abx448894-100ug 100 ug
EUR 661.2

Metallothionein Antibody

abx448894-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody

abx448894-596tests 5 × 96 tests Ask for price

Metallothionein Antibody

abx448894-96tests 96 tests
EUR 550

Metallothionein Antibody

abx448912-100ug 100 ug
EUR 661.2

Metallothionein Antibody

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Metallothionein Antibody

abx448912-596tests 5 × 96 tests Ask for price

Metallothionein Antibody

abx448912-96tests 96 tests
EUR 550

Metallothionein Antibody

abx448930-100ug 100 ug
EUR 661.2

Metallothionein Antibody

abx448930-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody

abx448930-596tests 5 × 96 tests Ask for price

Metallothionein Antibody

abx448930-96tests 96 tests
EUR 550

Metallothionein Antibody

GWB-38FF18 0.05 mg Ask for price

Metallothionein Antibody

MBS8000355-01mg 0.1mg
EUR 520

Metallothionein Antibody

MBS8000355-5x01mg 5x0.1mg
EUR 1785

Metallothionein Antibody

SMC-551D 0.1mg
EUR 231
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SMC-551S 0.012mg Ask for price
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SMC-552D 0.1mg
EUR 231
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SMC-552S 0.012mg Ask for price
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SMC-553D 0.1mg
EUR 231
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SMC-553S 0.012mg Ask for price
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody

SPC-717D 0.1mg
EUR 231.7
Description: Rabbit Anti-Pseudomonas aeruginosa Metallothionein Polyclonal

Metallothionein Antibody

SPC-717S 0.012mg Ask for price
Description: Rabbit Anti-Pseudomonas aeruginosa Metallothionein Polyclonal

MT2a | Metallothionein 2a

AS13-2685 50 µg
EUR 302

Metallothionein-1X Antibody

abx110454-100l 100 µl
EUR 162.5

Metallothionein-1X Antibody

20-abx110454
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Human Metallothionein-3 (MT3)

1-CSB-EP015122HU
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Description: Recombinant Human Metallothionein-3(MT3) expressed in E.coli

Human Metallothionein-3 (MT3)

1-CSB-EP015122HUe0
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Description: Recombinant Human Metallothionein-3(MT3) expressed in E.coli

Human Metallothionein-4 (MT4)

1-CSB-EP015123HU
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Description: Recombinant Human Metallothionein-4(MT4) expressed in E.coli

MT1a | Metallothionein type1

AS13-2684 50 µg
EUR 302

Human Metallothionein-2 (MT2A)

1-CSB-RP173544h
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Description: Recombinant Human Metallothionein-2(MT2A),partial expressed in E.coli

Human Metallothionein-2 (MT2A)

1-CSB-YP015120HU
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Description: Recombinant Human Metallothionein-2(MT2A),partial expressed in Yeast

Metallothionein 2 Antibody

20-abx101544
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Metallothionein Antibody (PE)

abx448910-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448910-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448910-96tests 96 tests
EUR 600

Metallothionein Antibody (PE)

abx448928-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448928-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448928-96tests 96 tests
EUR 600

Metallothionein Antibody (PE)

abx448946-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448946-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (PE)

abx448946-96tests 96 tests
EUR 600

Human Metallothionein-1X (MT1X)

1-CSB-EP015119HU
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Description: Recombinant Human Metallothionein-1X(MT1X),partial expressed in E.coli

Human Metallothionein-1E (MT1E)

1-CSB-RP173644h
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Description: Recombinant Human Metallothionein-1E(MT1E),partial expressed in E.coli

Human Metallothionein-1G (MT1G)

1-CSB-RP173844h
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Description: Recombinant Human Metallothionein-1G(MT1G),partial expressed in E.coli

Human Metallothionein-1A (MT1A)

1-CSB-RP174444h
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Description: Recombinant Human Metallothionein-1A(MT1A),partial expressed in E.coli

Human Metallothionein-1F (MT1F)

1-CSB-YP015112HU
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  • 1MG
Description: Recombinant Human Metallothionein-1F(MT1F),partial expressed in Yeast

Metallothionein Antibody (HRP)

abx448226-100ug 100 ug
EUR 678

Metallothionein Antibody (HRP)

abx448226-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448226-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448226-96tests 96 tests
EUR 600

Metallothionein Antibody (APC)

abx448904-100ug 100 ug
EUR 727.2

Metallothionein Antibody (APC)

abx448904-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (APC)

abx448904-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (APC)

abx448904-96tests 96 tests
EUR 612.5

Metallothionein Antibody (HRP)

abx448907-100ug 100 ug
EUR 710.4

Metallothionein Antibody (HRP)

abx448907-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448907-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448907-96tests 96 tests
EUR 600

Metallothionein Antibody (RPE)

abx448910-100ug 100 ug
EUR 727.2

Metallothionein Antibody (APC)

abx448922-100ug 100 ug
EUR 727.2

Metallothionein Antibody (HRP)

abx448925-100ug 100 ug
EUR 710.4

Metallothionein Antibody (HRP)

abx448925-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448925-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448925-96tests 96 tests
EUR 600

Metallothionein Antibody (RPE)

abx448928-100ug 100 ug
EUR 727.2

Metallothionein Antibody (APC)

abx448940-100ug 100 ug
EUR 727.2

Metallothionein Antibody (HRP)

abx448943-100ug 100 ug
EUR 710.4

Metallothionein Antibody (HRP)

abx448943-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448943-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (HRP)

abx448943-96tests 96 tests
EUR 600

Metallothionein Antibody (RPE)

abx448946-100ug 100 ug
EUR 727.2

Metallothionein Antibody: HRP

MBS8000368-01mg 0.1mg
EUR 555

Metallothionein Antibody: HRP

MBS8000368-5x01mg 5x0.1mg
EUR 1970

Metallothionein Antibody: RPE

MBS8000371-01mg 0.1mg
EUR 565

Metallothionein Antibody: RPE

MBS8000371-5x01mg 5x0.1mg
EUR 2010

Metallothionein Antibody: APC

SMC-551D-APC 0.1mg
EUR 267.4
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: HRP

SMC-551D-HRP 0.1mg
EUR 259
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: RPE

SMC-551D-RPE 0.1mg
EUR 266
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: APC

SMC-552D-APC 0.1mg
EUR 267.4
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: HRP

SMC-552D-HRP 0.1mg
EUR 259
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: RPE

SMC-552D-RPE 0.1mg
EUR 266
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: APC

SMC-553D-APC 0.1mg
EUR 267.4
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: HRP

SMC-553D-HRP 0.1mg
EUR 259
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: RPE

SMC-553D-RPE 0.1mg
EUR 266
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: APC

SPC-717D-APC 0.1mg
EUR 268.1
Description: Rabbit Anti-Pseudomonas aeruginosa Metallothionein Polyclonal

Metallothionein Antibody: HRP

SPC-717D-HRP 0.1mg
EUR 259.7
Description: Rabbit Anti-Pseudomonas aeruginosa Metallothionein Polyclonal

Metallothionein Antibody: RPE

SPC-717D-RPE 0.1mg
EUR 266.7
Description: Rabbit Anti-Pseudomonas aeruginosa Metallothionein Polyclonal

Metallothionein-2 (MT2) Antibody

abx130198-100l 100 µl
EUR 275

Metallothionein-2 (MT2) Antibody

abx130198-1ml 1 ml
EUR 775

Metallothionein-2 (MT2) Antibody

abx130198-200l 200 µl
EUR 350

Metallothionein-2 (MT2) Antibody

abx177539-96tests 96 tests
EUR 262.5

Metallothionein-4 (MT4) Antibody

abx306606-100g 100 µg
EUR 362.5

Metallothionein-4 (MT4) Antibody

20-abx306606
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Metallothionein-4 (MT4) Antibody

abx306606-20g 20 µg
EUR 162.5

Metallothionein-4 (MT4) Antibody

abx306606-50g 50 µg
EUR 250

Metallothionein-1 (rabbit liver)

MBS566101-1mg 1mg
EUR 610

Metallothionein-1 (rabbit liver)

MBS566101-5x1mg 5x1mg
EUR 2600

Rat Metallothionein 1 ELISA

E01A14833 96T
EUR 700
Description: ELISA

Rat Metallothionein 1 ELISA

E02M0551-48wellsplate 48 wells plate
EUR 280

Rat Metallothionein 1 ELISA

E02M0551-96wellsplate 96 wells plate
EUR 405

Metallothionein Antibody (FITC)

abx448224-100ug 100 ug
EUR 678

Metallothionein Antibody (FITC)

abx448224-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448224-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448224-96tests 96 tests
EUR 600

Metallothionein (mymT) Antibody

abx448560-100ug 100 ug
EUR 627.6

Metallothionein (mymT) Antibody

abx448560-1096tests 10 × 96 tests Ask for price

Metallothionein (mymT) Antibody

abx448560-596tests 5 × 96 tests Ask for price

Metallothionein (mymT) Antibody

abx448560-96tests 96 tests
EUR 550

Metallothionein Antibody (FITC)

abx448906-100ug 100 ug
EUR 727.2

Metallothionein Antibody (FITC)

abx448906-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448906-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448906-96tests 96 tests
EUR 600

Metallothionein Antibody (FITC)

abx448924-100ug 100 ug
EUR 727.2

Metallothionein Antibody (FITC)

abx448924-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448924-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448924-96tests 96 tests
EUR 600

Metallothionein Antibody (FITC)

abx448942-100ug 100 ug
EUR 727.2

Metallothionein Antibody (FITC)

abx448942-1096tests 10 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448942-596tests 5 × 96 tests Ask for price

Metallothionein Antibody (FITC)

abx448942-96tests 96 tests
EUR 600

Metallothionein Antibody: FITC

MBS8000367-01mg 0.1mg
EUR 560

Metallothionein Antibody: FITC

MBS8000367-5x01mg 5x0.1mg
EUR 1990

Metallothionein Antibody: FITC

SMC-551D-FITC 0.1mg
EUR 261.8
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

Metallothionein Antibody: FITC

SMC-552D-FITC 0.1mg
EUR 261.8
Description: Mouse Anti-Pseudomonas aeruginosa Metallothionein Monoclonal IgG1

We revealed wide variation in genome size and investigate the molecular processes that underlie this variation. We showed an unexpected complexity in the evolutionary history of genes key to the development path. The new species and resources related genomes will be critical in our efforts to understand the origin of the evolution of C. elegans Model.