Protacs Medchemexpress

Human Centriole and Centrosome Antibody IgG ELISA Kit
MBS039049-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human IgG antibody Laboratories manufactures the protacs medchemexpress reagents distributed by Genprice. The Protacs Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Protacs products are available in stock. Specificity: Protacs Category: Medchemexpress

Human True Insulin ELISA Kit
5x96-Strip-Wells
EUR 3420

Human True Insulin ELISA Kit
96-Strip-Wells
EUR 765

Human True Insulin GENLISA ELISA
1 x 96 wells
EUR 286

Human True insulin ELISA kit
96T
EUR 700
Description: ELISA

Human True insulin ELISA kit
192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human True insulin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human True insulin ELISA kit
1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human True insulin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human True insulin ELISA kit
48 wells plate
EUR 280

Chemicals information

PROTAC Axl Degrader 2
HY-144627 10 mg
EUR 4491.41
Description: PROTAC Axl Degrader 2 is a potent and selective PROTAC Axl degrader with an IC50 of 1.61 µM. PROTAC Axl Degrader 2 shows anti-proliferation activity, anti-migration activity in vitro. PROTAC Axl Degrader 2 induces mehuosis[1].

PROTAC BTK Degrader-3
HY-153536 Get quote Ask for price
Description: PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].

PROTAC EGFR degrader 8
HY-153901 Get quote Ask for price
Description: PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].

PROTAC BTK Degrader-6
HY-149391 Get quote Ask for price
Description: PROTAC BTK Degrader-6 (Compound 15) is a PROTAC BTK degrader (DC50: 3.18 nM. PROTAC BTK Degrader-6 has anti-inflammatory activity, inhibits NF-κB activation, and inhibits the expression of pro-inflammatory cytokines (e.g. IL-1β, IL-6)[1].

PROTAC BET Degrader-1
HY-103633 25mg
EUR 595.25
Description: PROTAC BET Degrader-1 is a PROTAC connected by ligands for Cereblon and BET, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration.

PROTAC B-Raf degrader 1
HY-111758 10mM/1mL
EUR 3084.46
Description: PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activity[1].

PROTAC RAR Degrader-1
HY-111844 1mg
EUR 595.25
Description: PROTAC RAR Degrader-1 comprises a IAP ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

PROTAC ERα Degrader-2
HY-111846 50mg
EUR 4545.53
Description: PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

PROTAC AR Degrader-4 (TFA)
HY-111848A 5 mg
EUR 1569.29
Description: PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

PROTAC ERα Degrader-1
HY-112098 10mM/1mL
EUR 8658.14
Description: PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha (ERα) degrader.

PROTAC ERα Degrader-5
HY-112100 1mg
EUR 2056.31
Description: PROTAC ERα Degrader-5 (compound LP2) consists an ADC linker and a PROTAC, whcih can be conjugated to an antibody to form PACs. PROTAC ERα Degrader-5 conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab)[1].

PROTAC BET degrader-2
HY-114228 25mg
EUR 2489.22
Description: PROTAC BET degrader-2 is a PROTAC connected by ligands for Cereblon and BET with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression.

PROTAC BET degrader-3
HY-114229 10mg
EUR 595.25
Description: PROTAC BET Degrader-3 is a PROTAC connected by ligands for von Hippel-Lindau and BET.

PROTAC FLT-3 degrader 1
HY-114323 1 mg
EUR 2164.54
Description: PROTAC FLT-3 degrader 1 is a von Hippel-Lindau-based PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

FKBP12 PROTAC dTAG-13
HY-114421 1 mg
EUR 3047.67
Description: FKBP12 PROTAC dTAG-13 (dTAG-13), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 effectively engages FKBP12F36V and CRBN, thereby selectively degrading FKBP12F36V[1].

PROTAC HK2 Degrader-1
HY-155008 1 mg
EUR 1689.42
Description: PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine (HY-B0486) as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide (HY-14658) as a CRBN ligand-linked PROTAC. PROTAC HK2 Degrader-1 selectively inhibits the proliferation of breast cancer cells by forming a ternary complex through the ubiquitin-proteasome system to degrade Hexokinase 2 (HK2) protein leading to mitochondrial damage and cell death. PROTAC HK2 Degrader-1 effectively inhibits breast tumor growth and reduces the colonic side effects of cisplatin for breast cancer research[1].

PROTAC BTK Degrader-5
HY-155072 Get quote Ask for price
Description: PROTAC BTK degraders-5(compound 3e) is a selective BTK degrader with a DC50 value of 7.0 nM in JeKo-1 cells. PROTAC BTK degraders-5 has no off-target effect on degrading CRBN neosubstates. PROTAC BTK degraders-5 has anti-proliferation effect on various lymphoma tumor cells and can be used in chronic lymphoid malignancies research1.