Mybiosource Lag-3

LAG-3 (LAG-3) Antibody
abx234676-100ug 100 ug
EUR 577.2

Human IgG antibody Laboratories manufactures the mybiosource lag-3 reagents distributed by Genprice. The Mybiosource Lag-3 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MyBiosource Eur. Other Mybiosource products are available in stock. Specificity: Mybiosource Category: Lag-3

LAG-3 Antibody [1C6]
0.1 mg
EUR 723.62
Description: The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.

LAG-3 Antibody [1A8]
0.02 mg
EUR 253.22
Description: The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.

LAG-3 Antibody [1A8]
0.1 mg
EUR 723.62
Description: The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.

LAG-3 ELISA KIT|Human
96 Tests
EUR 826.8

JBS True Blue
300 µl
EUR 16
Description: JBS True Blue

LAG-3 Recombinant Protein
0.05 mg
EUR 588.3
Description: Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.

LAG-3 Recombinant Protein
0.05 mg
EUR 739.5
Description: Lymphocyte-activation gene 3 (LAG3), also known as CD223, is a type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4 and belongs to the immunoglobulin superfamily. The gene for LAG3 lies adjacent to the gene for CD4 on human chromosome 12p13.32 and shares approximately 20% identical to the CD4 gene. LAG3 is expressed on activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. LAG3 binds with high affinity to MHC class II molecules, and it interferes competitively with the binding of CD4 to MHC class II and thereby blocks the transduction of stimulatory signals mediated by this interaction. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and plays an important role in Treg suppressive function. LAG3 is the target of various drug development programs to develop new treatments for cancer and autoimmune disorders. The soluble form, sLAG-3, is being developed as a cancer drug.

Chemicals information

Recombinant Mouse LAG-3/CD223 Protein
RP00678 10 μg
EUR 265.2

LAG 1 protein
30R-AL016 20 ug
EUR 327.6
Description: Purified recombinant Human LAG 1 protein

Mouse Anti-Human CD233 (LAG-3) mAb
CM087-100ug 100ug
EUR 555.6

Mouse Anti-Human CD233 (LAG-3) mAb
CM087-25ug 25ug
EUR 285.6

Mouse Anti-Human CD233 (LAG-3) mAb
CM088-100ug 100ug
EUR 555.6

Mouse Anti-Human CD233 (LAG-3) mAb
CM088-25ug 25ug
EUR 285.6

Recombinant Human LAG-3/CD233 (C-Fc)
CU30-10ug 10ug
EUR 169.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (C-Fc)
CU30-1mg 1mg
EUR 2008.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (C-Fc)
CU30-500ug 500ug
EUR 1423.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (C-Fc)
CU30-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

LAG-1 (CCL4L1) Protein
20-abx260659
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

LAG-1 (CCL4L1) Protein
20-abx262061
  • EUR 5755.20
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Recombinant Human LAG-3/CD233 (Leu23-Leu450)
CU29-10ug 10ug
EUR 169.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (Leu23-Leu450)
CU29-1mg 1mg
EUR 2008.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (Leu23-Leu450)
CU29-500ug 500ug
EUR 1423.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human LAG-3/CD233 (Leu23-Leu450)
CU29-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

LAG-1 Recombinant Protein
40-406-0005mg 0.005 mg
EUR 311.1
Description: LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.