MK-7145 |
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HY-18277 |
MedChemExpress |
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Description: MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. |
Human IgG antibody Laboratories manufactures the mk-7145 medchemexpress reagents distributed by Genprice. The Mk-7145 Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Mk-7145 products are available in stock. Specificity: Mk-7145 Category: Medchemexpress
Chemicals information
MK-0159 |
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HY-150508 |
MedChemExpress |
10 mg |
EUR 833.35 |
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Description: MK-0159 is an orally active, potent and selective CD38 inhibitor, with IC50 values of 22, 3, and 70 nM for human, mouse and rat CD38, respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD+ (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart[1]. |
MK-4101 |
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HY-100036 |
MedChemExpress |
100mg |
EUR 411.26 |
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Description: MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 µM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 µM for mouse cells; IC50 of 1 µM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis[1]. |
MK-3328 |
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HY-100275 |
MedChemExpress |
1mg |
EUR 617.98 |
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Description: MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM[1][2]. |
MK-447 |
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HY-100297 |
MedChemExpress |
10mg |
EUR 2047.2 |
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Description: MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins. |
MK-6913 |
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HY-100327 |
MedChemExpress |
10mg |
EUR 7346.4 |
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Description: MK-6913 (Tetrahydrofluoroene 52) is a potent and selective estrogen receptor β agonist. |
MK-8617 |
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HY-101023 |
MedChemExpress |
50mg |
EUR 443.73 |
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Description: MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) with an IC50 of 1 nM for PHD2. |
MK-212 |
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HY-101324 |
MedChemExpress |
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Description: MK-212 (CPP) is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 can stimulate phosphoinositide hydrolysis in cerebral cortex[1]. |
MK-0343 |
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HY-101869 |
MedChemExpress |
10 mg |
EUR 865.81 |
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Description: MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic[1]. |
MK-0608 |
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HY-10244 |
MedChemExpress |
10 mg |
EUR 1190.49 |
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Description: MK-0608 is a potent and orally bioavailable inhibitor of HCV replication in vitro with an EC50 of 0.3 μM (EC90=1.3 μM) in the subgenomic-replicon assay[1]. |
MK-0674 |
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HY-10290 |
MedChemExpress |
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Description: MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S[1]. |
MK-3207 |
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HY-10301 |
MedChemExpress |
5mg |
EUR 207.8 |
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Description: MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC50=0.12 nM; Ki=0.024 nM). MK-3207 can be used for migraine studies[1]. |
MK-2894 |
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HY-10413 |
MedChemExpress |
50mg |
EUR 1402.62 |
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Description: MK-2894 is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis[1][2]. |
MK-6892 |
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HY-10680 |
MedChemExpress |
100mg |
EUR 1168.85 |
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Description: MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A. Ki and GTPγS EC50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively. |
MK 386 |
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HY-106951 |
MedChemExpress |
1mg |
EUR 628.8 |
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Description: MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1]. |
