MK-7145 |
HY-18277 |
MedChemExpress |
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Description: MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. |
Human IgG antibody Laboratories manufactures the mk-7145 medchemexpress reagents distributed by Genprice. The Mk-7145 Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Mk-7145 products are available in stock. Specificity: Mk-7145 Category: Medchemexpress
Chemicals information
MK-447 |
HY-100297 |
MedChemExpress |
10mg |
EUR 2047.2 |
Description: MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins. |
MK-6913 |
HY-100327 |
MedChemExpress |
10mg |
EUR 7346.4 |
Description: MK-6913 (Tetrahydrofluoroene 52) is a potent and selective estrogen receptor β agonist. |
MK-8617 |
HY-101023 |
MedChemExpress |
50mg |
EUR 443.73 |
Description: MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) with an IC50 of 1 nM for PHD2. |
MK-212 |
HY-101324 |
MedChemExpress |
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Description: MK-212 (CPP) is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 can stimulate phosphoinositide hydrolysis in cerebral cortex[1]. |
MK-4541 |
HY-125065 |
MedChemExpress |
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Description: MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model[1]. |
MK-4101 |
HY-100036 |
MedChemExpress |
100mg |
EUR 411.26 |
Description: MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 µM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 µM for mouse cells; IC50 of 1 µM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis[1]. |
MK 0893 |
HY-50663 |
MedChemExpress |
10mM/1mL |
EUR 1850.68 |
Description: MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM. |
MK-0812 |
HY-50669 |
MedChemExpress |
5mg |
EUR 194.81 |
Description: MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2. |
MK-0731 |
HY-50672 |
MedChemExpress |
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Description: MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy[1][2]. |
MK-1903 |
HY-107581 |
MedChemExpress |
10 mg |
EUR 919.93 |
Description: MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1]. |
MK-4074 |
HY-107709 |
MedChemExpress |
10mM/1mL |
EUR 1298.72 |
Description: MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM. |
MK-3903 |
HY-107988 |
MedChemExpress |
10mM/1mL |
EUR 487.02 |
Description: MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator with an EC50 of 8 nM. |
MK-2206 |
HY-108232 |
MedChemExpress |
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Description: MK-2206 is an orally active, highly potent and selective allosteric Akt inhibitor, with IC50s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206. MK-2206 has anticancer activities[1][2]. |
MK-0752 |
HY-10974 |
MedChemExpress |
100mg |
EUR 970.79 |
Description: MK-0752 is a potent, orally active and specific γ-secretase inhibitor, showing dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS Aβ in vivo[1][2]. |