BMS-345541 |
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abx282828-100g |
Abbexa |
100 µg |
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Human IgG antibody Laboratories manufactures the bms-345541 medchemexpress reagents distributed by Genprice. The Bms-345541 Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Bms-345541 products are available in stock. Specificity: Bms-345541 Category: Medchemexpress
Chemicals information
BMS-986339 |
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HY-150787 |
MedChemExpress |
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Description: BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues. BMS-986339 can be used in the research of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH), anti-fibrosis[1]. |
BMS-986141 |
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HY-150790 |
MedChemExpress |
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Description: BMS-98614 is an orally active, selective thrombin receptor protease-activated receptor-4 (PAR-4) antagonist with an IC50 value of 0.4 nM. BMS-98614 has excellent antithrombotic effect[1][2]. |
BMS-911543 |
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HY-15270 |
MedChemExpress |
10mM/1mL |
EUR 1000.02 |
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Description: BMS-911543 is a selective JAK2 inhibitor, with IC50s of 1.1 nM, less selective at JAK1, JAK3 and TYK2 (IC50, 75, 360, 66 nM, respectively). |
BMS-265246 |
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HY-15275 |
MedChemExpress |
100mg |
EUR 865.81 |
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Description: BMS-265246 is a potent and selective cyclin-dependent kinase CDK1 and CDK2 inhibitor, with IC50 values of 6 and 9 nM, respectively. BMS-265246 inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). BMS-265246 can be used for ovarian cancer and COVID-19 research[1][2][3]. |
BMS-986251 |
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HY-136527 |
MedChemExpress |
1 mg |
EUR 11174.42 |
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Description: BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced (HY-B0180) models (preclinical models of psoriasis)[1]. |
BMS-833923 |
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HY-13809 |
MedChemExpress |
100mg |
EUR 277.06 |
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Description: BMS-833923 (XL-139) is an orally biocompatible Smoothened (Smo) inhibitor with anti-tumor activity. It can inhibit the binding of BODIPY cyclopamine to SMO in a dose-dependent manner with an IC50 of 21 nM[1]. |
BMS-585248 |
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HY-13829 |
MedChemExpress |
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Description: BMS-585248 is a potent, third-generation HIV-1 attachment inhibitor with a promising initial in vitro and in vivo pharmacokinetic profile[1]. |
BMS-795311 |
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HY-19614 |
MedChemExpress |
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Description: BMS-795311 is a potent and orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP), with IC50s of 4 nM in an enzyme-based scintillation proximity assay (SPA) and 0.22 μM in a human whole plasma assay (hWPA), respectively[1]. |
BMS-561392 |
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HY-19667 |
MedChemExpress |
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Description: BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. BMS-561392 is also an ADAM17 blocker. BMS-561392 can be used for research of inflammatory bowel disease[1][2]. |
BMS-986120 |
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HY-19837 |
MedChemExpress |
10 mg |
EUR 1839.86 |
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Description: BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist, with IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatelet effects[1][2]. |
BMS-779788 |
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HY-19919 |
MedChemExpress |
2mg |
EUR 346.33 |
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Description: BMS-779788 is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ. |
BMS-986172 |
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HY-149663 |
MedChemExpress |
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Description: BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1]. |
BMS-986176 |
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HY-134829 |
MedChemExpress |
1 mg |
EUR 2759.78 |
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Description: BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases research[1]. |
BMS-986020 |
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HY-100619 |
MedChemExpress |
10mM/1mL |
EUR 487.02 |
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Description: BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist[1]. BMS-986020 inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively[2]. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF)[3]. |
